Clinical Chemistry III-Endocrinology, Toxicology and Drug Testing
Endocrinology is a part of our physiologic regulatory system, the collection of hormones, proteins and other components and other processes form the endocrine system. The Endocrine System is consists of many ductless glands that produce highly active chemical regulators called "hormone.
1. It is a substances which can be secreted and produced into the blood by an tissue or an organ.
2. It has a target tissue which is located away from the site of hormones.
3. It promote production and release certain other hormones.
4. Regulate energy production
Toxicology is a study of poisonous toxic drugs. The substance that when taken in sufficient quantity which causes death is toxicant. Toxicity is well defined as"super or extremely" toxic.
Factors that Influence Toxicity
1. Physical State and Solubility
2. Exposure of different toxicant(route, exposure)
3. Toxicokinetics of the toxicant by metabolic processes.
Drug Testing
- it is used to confirm drugs which found in patients serum or urine etc. using drug- screening method.Gas Chromatography is normally used to confirm drugs detected by screening techniques.
Kinds of Drug Testing
1.Urine Drug Testing
2. Hair Drug Testing
3.Oral/Saliva Drug Testing
4. Surface Drug Detection Wipes